#1133 - Dennis McKenna cover

#1133 - Dennis McKenna

NaN minutesEpisode #1133

Dennis McKenna is an ethnopharmacologist, author, and brother to well-known psychedelics proponent Terence McKenna. His new book "Ethnopharmacologic Search for Psychoactive Drugs: 50 Years of Research (1967-2017)" is available here:

Watch the full episode of #1133 - Dennis McKenna.

Episode Timestamps

  • Institute for Eco Technics - The Hippie Ship Heraclitus and Biosphere 2

    • The RV Heraclitus, associated with the Institute for Eco Technics, embarked on global ecological exploration since 1973.
    • Transitioned to ambitious projects like Biosphere 2; a self-sustaining terrestrial environment.
    • Encountered criticism and adverse publicity but contributed significantly to science; also involved in art and publishing ventures.
  • Ethno-Pharmacologic Search for Psychoactive Drugs - From 1967 to 2017

    • Discussion on the genesis of a book from a 1967 private conference on ethnopharmacology.
    • Impact of influential figures like Schultes and Shulgin on the field of ethno-pharmacology.
    • Personal journey and career influence from early exposure to the book, highlighting the psychedelic research landscape.
  • Exploring Psychedelic Pioneers: Steven Zara and the 67 Conference

    • 67 book was significant for bringing leading experts together, including iconic individuals like Shultes, Weil, and Shulgin
    • Presentation on Steven Zara, a chemist and psychiatrist, at the first conference showcased his pioneering self-experimentation with DMT
    • Zara's involvement in showcasing DMT as a psychedelic and his post-conference experiences shed light on the evolution of psychedelic research
  • Psychedelic Research Evolution: From the 67 Conference to Present Day

    • The 50th-anniversary conference in 2017 marked a milestone in psychedelic research, highlighting advancements compared to the 67 conference
    • Increased accessibility through Facebook live streaming and widespread audience engagement revolutionized information dissemination
    • Discussion on the impact of psychedelics on spiritual exploration, societal perspectives, and the need for environmental consciousness
  • Michael Pollan's Missed Opportunities

    • Author expresses disappointment in Michael Pollan's book for not emphasizing indigenous traditions
    • Discusses Pollan's oversight of not exploring the historical significance of psychedelics beyond LSD discovery
    • Highlights the author's jealousy and frustration for not being consulted despite having valuable insights
  • The Impact and Potential of Psychedelics

    • Acknowledges the potential influence of Pollan's book in raising awareness about psychedelics
    • Explores the resurgence of psychedelics and its role in challenging preconceived notions
    • Discusses the transformative effects of psychedelics on perception and consciousness, emphasizing their educational and societal value
  • McKenna Academy for Natural Philosophy: Future of Psychedelic Education

    • Establishment of the McKenna Academy for Natural Philosophy as the first psychedelic university in the Western tradition
    • Structured courses, degrees, therapeutic programs, and impactful global conferences planned
    • Emphasis on natural philosophy to explore phenomena beyond traditional scientific constraints
  • Psychedelics, Parapsychology, and the Legacy of Terence McKenna

    • Challenges in investigating paranormal phenomena like UFOs and altered states acknowledged
    • Critique of mainstream science's dogmatism and dismissal of unconventional topics
    • Recognition of Terence McKenna as a pioneer in psychedelic advocacy and shaping public discourse
  • Terence McKenna & Time Wave Zero

    • Terence McKenna developed Time Wave Zero which was based on an algorithm and oracle of 64 hexagrams
    • The Time Wave was believed to predict the ingression of novelty into the continuum
    • McKenna and others debated its effectiveness in describing novelty
  • DMT & Extraterrestrial Connections

    • Discussion on DMT and its potential origin from extraterrestrial sources
    • The connection of DMT to tryptophan and other psychedelic tryptamines
    • Exploration of the common presence of DMT in nature and its widespread existence in various plants and organisms
  • Discovery of Harming Alkaloid and Its Neurogenic Effects

    • Harming, an MAO inhibitor, was discovered in Paganum Harmola before ayahuasca, showing interesting pharmacological effects.
    • Harming is known to stimulate neurogenesis, relevant to conditions like Alzheimer's and Down Syndrome.
    • Researchers identified its inhibition of the regulatory protein DYRK1 and its interaction with various receptors like serotonin and dopamine transporters.
  • Confusion and Misnaming in Early Ayahuasca Research

    • Early researchers misnamed certain molecules in ayahuasca due to lack of coordination and failure to collect voucher specimens.
    • Later Chinese scientists discovered the main alkaloids in harmala and established their botanical references.
    • Misnomers like telepathine indicated a romanticized belief in telepathic experiences linked to these substances, though lacking concrete evidence.
  • Whitley Streber's Unexplained Encounters

    • Whitley shares his personal encounters and experiences with alternate realities
    • Jeffrey provides explanations linking the phenomena to mythology and reasonable interpretations
    • Their book explores the physical explanation of unexplained events, discussing concepts like 'the soul as a UFO'
  • Exploring the Connection between Dream States and UFO Abductions

    • Discussion on the correlation between UFO abductions and dream states
    • Debate on the role of endogenous chemicals and psychedelic experiences in these encounters
    • Reflecting on the balance between accepting unexplained phenomena and scientific inquiry
  • Exploring DMT and Natural Philosophy

    • Contemplating the origin of hallucinogenic experiences like DMT and questioning if it originates solely within the brain or if it removes filters from the eyes.
    • Highlighting the humility in natural philosophy to acknowledge the unknown, contrasting it with science's arrogance in claiming to know all.
    • Discussion on controversies surrounding the endogenous production of DMT and its effects on the brain as debated by researchers like David Nichols.
  • Discovery of DMT and Novel Experiences with Ajna Light

    • Debating the controversy regarding endogenous DMT production and the role of the pineal gland in secreting DMT under certain conditions.
    • Exploring the innovative Ajna Light device and its purported ability to stimulate DMT synthesis in the brain through unique hypnagogic experiences.
    • Discussion on the challenges of studying DMT's effects due to its rapid breakdown in the system and innovative research methods like micro capillary tube placement near the pineal gland.
  • Exploring Edible Marijuana in Darkness with Dennis

    • Discusses the experience of consuming edible marijuana in complete darkness
    • Shares the profound and visual effects of high doses of edible marijuana
    • Mentions an open invitation from Dennis to experience immersion tech
  • From Minnesota to British Columbia with Donald Trump Influence

    • Reveals the decision to move from Minnesota to British Columbia
    • Cites Donald Trump's influence on the decision to immigrate to Canada
    • Shares plans related to teaching, residence, and upcoming expeditions in South America
  • Exploring Sustainable Agriculture Initiatives in Sacred Valley, Peru

    • Discussing involvement of local communities and smart doctors in sustainable agriculture projects in Peru
    • Highlighting Sacred Valley as a hub of agricultural diversity with thousands of unique plant varieties
    • Emphasizing the potential solutions to global food crisis through genetic repository of agricultural products
  • Advancements in Ethno-Pharmacologic Search for Psychoactive Drugs and Legalization Efforts in Canada

    • Proposing standardized ingredients list for ayahuasca dosage along with exploration of other medicinal plants
    • Discussing the search for psychoactive drug discoveries and the legalization of marijuana in Canada
    • Detailing the initiatives to legalize psychedelics for therapeutic uses in Canada, focusing on MDMA-assisted psychotherapy trials and policy changes
  • Reflection on Trump's Impact on Society and Individual Growth

    • Discussion about Trump's lack of reflection and impulsivity
    • Exploring assumptions about personal growth and learning at different ages
    • Impact of psychedelics on neuroplasticity and changing brain connections
  • Social and Political Implications of Trump's Presidency

    • Trump viewed as a disruptor of the political system
    • Critique of the broken system and the concept of 'draining the swamp'
    • Reflections on potential consequences of technological advancements on human existence
  • Future of Humanity: Symbiosis with Technology

    • Prediction of symbiosis between humans and complex electronics in the future
    • Discussion on the moral implications of technological advancements
    • Importance of psychedelics in aligning cleverness with wisdom
  • Evolution into the Technological Butterfly

    • Speculation on the creation of artificial life and merging with technology
    • Ethical concerns around technological advancements and the importance of moral compass
    • The potential for humanity to transform into a new form beyond human
  • Psychedelics as Teachers for a Humanistic Culture

    • Psychedelics can be catalysts for teaching us to love ourselves, each other, and the earth
    • They offer a promise of helping us become the human beings we aspire to be
    • Alternative to a hyper-technological future, emphasizing wisdom in technology use
  • Promise of Psychedelics: Maximizing Human Potential

    • Psychedelics hold the promise of maximizing human potential and humanity
    • Focus on deploying technologies to enhance human capacities
    • Hopes for creating spaces where people can learn and grow towards a positive future
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