#2301 - Ben Lamm cover

#2301 - Ben Lamm

187 minutesEpisode #2301

Ben Lamm is a serial entrepreneur and the founder and CEO of Colossal Biosciences, a company dedicated to genetic engineering and de-extinction projects. Colossal’s mission includes bringing back extinct species like the woolly mammoth and advancing conservation efforts through cutting-edge biotechnology. www.colossal.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

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Key Takeaways

Colossal Biosciences is pioneering de-extinction efforts for ecological benefits.

This approach could reshape conservation strategies and biodiversity management.

The relationship between ancient mammoths and modern elephants reveals genetic insights.

Understanding these connections enhances our knowledge of species evolution and conservation.

The potential for de-extinction is growing through advanced genetic techniques.

This could reshape our understanding of extinct species and biodiversity.

Collaboration between researchers and institutions is crucial for successful expeditions.

Such partnerships enhance resource access and knowledge sharing in scientific endeavors.

The creation of woolly mice demonstrates advanced genetic editing techniques.

This represents a significant step in understanding genetic engineering and de-extinction.

Episode Timestamps

  • Exploring De-Extinction: Reviving Mammoths and Conservation Technologies

    • Colossal Biosciences aims to bring back extinct species like mammoths.
    • Innovative use of AI and synthetic biology is key to de-extinction efforts.
    • Mammoths could play a vital role in ecosystem restoration and conservation.
  • Exploring Mammoth Retrieval and Genetic Research Innovations

    • Discussion centers on expeditions to retrieve mammoth remains in Alaska.
    • John, a significant figure, is deeply involved in mammoth research and expeditions.
    • Synthetic biology's role in de-extinction of species like the woolly mammoth is highlighted.
  • Genetic Engineering of Woolly Mice Sparks Excitement and Controversy

    • Geneticists are using ancient DNA to create woolly mice as a proof of concept.
    • The project aims to explore de-extinction techniques and educate the public.
    • Concerns about genetic editing and animal welfare are prominent in discussions.
  • Exploring the Ethics of Rewilding and Ecosystem Restoration

    • The discussion centers on the ecological impacts of reintroducing species like wolves.
    • Concerns arise over the balance between human agriculture and wildlife restoration efforts.
    • The dialogue emphasizes the need for thoughtful ecological management and monitoring.
  • Discussion on Wolves, Rewilding, and Human Perception

    • Only 0.02% deaths of livestock are attributed to wolves in Colorado.
    • Rewilding programs face challenges due to human misconceptions and economic interests.
    • Emotional connections and historical narratives shape our views on wolves and wildlife.
  • Exploring Animal Behavior and Genetic Ancestry in Modern Contexts

    • Discussion on the reawakening of ancient hunting genes in animals.
    • Insights into animal husbandry and the complexities of feeding practices.
    • Examination of theories surrounding megafauna extinction and environmental changes.
  • Navigating the Tensions Between Academia and Innovative Science

    • Academia struggles to support bold scientific innovations due to rigid structures.
    • The conflict between established scientific norms and new ideas is highlighted.
    • Funding and political biases significantly impact scientific research and progress.
  • Discussion on De-extinction and Genetic Modification of Animals

    • Exploration of genetic modification and its potential ecological impacts on species.
    • Debate over definitions of species and the implications for conservation efforts.
    • Open-source technology initiatives aimed at animal conservation and genetic diversity.
  • Discussing Extinction and the Possibility of De-Extinction

    • The rapid extinction of North American megafauna is influenced by multiple factors.
    • Saber-toothed cats and dire wolves are popular candidates for de-extinction efforts.
    • The conversation highlights the fascination with ancient creatures and their biology.
  • Artificial Wombs and the Future of Species Rewilding

    • The potential for artificial wombs to aid in species conservation is discussed.
    • Concerns about ethical implications of creating life in artificial environments arise.
    • The conversation highlights the importance of collaboration in rewilding efforts.
  • Exploring Animal Behavior and Human Phobias Through Ecological Studies

    • Research on thylacines reveals generational trauma influencing animal behavior.
    • Human fears, like arachnophobia, may stem from ancestral experiences.
    • Ecologists utilize innovative methods like camera traps for wildlife studies.
  • Discussion on Health, Diet, and Aging Insights

    • The conversation highlights the link between inflammation and Alzheimer's disease.
    • Emphasis on the importance of diet and exercise for health and longevity.
    • Unique insights into the popularity of consuming extinct species and its implications.
  • Exploring Extinct Species and Their Ecological Impact

    • Discussion about the potential reintroduction of the Tasmanian tiger into ecosystems.
    • Overview of unique prehistoric species like giant beavers and American cheetahs.
    • The role of invasive species in Australia's extinction rates and ecosystem balance.
  • Genetic Engineering's Role in Conservation and Evolution

    • Cane toads threaten quolls, prompting genetic engineering for species survival.
    • Research reveals potential for engineered quolls to resist cane toad neurotoxins.
    • Concerns arise over ethical implications of genetic modifications in conservation efforts.
  • Exploring Genetic Engineering and Human Enhancement in Society

    • Discussion on gene editing technology and its implications for human intelligence.
    • Concerns raised about ethical issues surrounding genetic manipulation and eugenics.
    • Speculation on future advancements in human enhancement and societal changes.
  • Exploring Longevity, Cloning, and the Ethics of Technology

    • Discussion on longevity technology faces barriers like ethics and FDA processes.
    • Cloning of pets raises ethical questions about loss and attachment.
    • Synthetic biology and AI may revolutionize healthcare and conservation efforts.
  • Exploring the Future of Synthetic Biology and AI

    • Synthetic biology has the potential to revolutionize environmental solutions through AI.
    • Concerns exist about unintended consequences of genetic engineering and rewilding.
    • China's advancements in synthetic biology highlight the global race for bioengineering technologies.
  • Exploration of Ancient Civilizations and Natural Catastrophes

    • The discussion centers around archaeological findings and ancient civilizations like the Mayans.
    • Controversial theories about historical events often face significant skepticism and backlash.
    • Connections are made between ancient texts and modern interpretations of natural disasters.
  • Exploring Advanced Technology and Human Evolution

    • Discussion on UFOs and advanced technology from experts like Hal Puthoff.
    • Speculation about human evolution influenced by advanced extraterrestrial beings.
    • Mention of ancient civilizations and their advanced understanding of the cosmos.

People Mentioned

Ben

Co-founder of Colossal Biosciences

Joe Rogan

Host of the podcast

John

Mammoth researcher, Board member of Explorers Club

+4 more

Unnamed Speaker

Discussion Participant

Kenneth Lacovara

Paleontologist

Bridget von Holt

Wolf geneticist

Unknown

Podcast Host/Guest

Unknown speaker

Podcast host or guest

Gary

Health expert, Influencer

+3 more

Bob Nelson

Founder of Arch Ventures

Jeff Bezos

Founder of Amazon

George Church

Co-founder of synthetic biology initiatives, Scientist and Biotechnologist

Graham Hancock

Historian, Author, Researcher, Author

Jimmy Corsetti

YouTube Creator, Ancient History Enthusiast

Hal Puthoff

Scientist, Researcher

Places Mentioned

Wrangell Island

Geographic location related to mammoth extinction.

+3 more

Alaska

Geographical location

Fairbanks

City

Yellowstone

National Park

+1 more

Colorado

State

+10 more

Central Tasmania

Location of ecological studies

Tokyo and Shanghai

Cities visited for business

Tasmania

Region

+13 more

Kruger National Park

National Park

Chichen Itza

Archaeological Site

+2 more

Reichardt structure

Archaeological Site

Books Mentioned

The Abolition of Man

C.S. Lewis

Notable Quotes

"It's essentially real-life Jurassic Park."

Describing Colossal Biosciences' mission.

"Mammoths could actually net benefit the ecosystem."

Discussing the ecological impact of reintroducing mammoths.

"That's awesome. Showed us skull."

Describing the impressive findings during an expedition.

"Nobody's put real capital now."

Discussing the funding challenges in de-extinction research.

"People lost minds, right? ... wants woolly mouse."

Discussion about public fascination with genetic engineering.

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