#1551 - Paul Saladino
NaN minutesEpisode #1551
Dr. Paul Saladino is a physician and board-certified nutrition specialist. He’s a leading expert in the science and practice of the carnivore diet, a food regimen to which Saladino credits numerous health benefits seen in the patients under his care.
Watch the full episode of #1551 - Paul Saladino.
Episode Timestamps
Dietary Perspectives: Meat vs. Plants
- Discussions on the benefits and controversies of a primarily meat-based diet
- Exploration of the co-evolution between plants and animals, and their defensive mechanisms
- Analysis of the argument that plants might not necessarily be as benign for human consumption as traditionally thought
Hormetic Responses and Molecular Hormesis
- Explanation of the concept of hormesis in response to plant compounds and other stressors like sauna or sunlight exposure
- Distinction between environmental and molecular hormesis in relation to human health
- Concerns regarding the potential side effects of exogenous plant compounds on human biochemistry
Harmful Effects of Plant Molecules on Thyroid and Antioxidant System
- Discussion on sulforaphane as a pro-oxidant that can negatively impact the human body
- Exploration of isothiocyanates damaging DNA and inhibiting iodine absorption, affecting the thyroid
- Anecdote of goiters in Africa due to goitrogenic foods affecting the thyroid and hormonal systems
Debunking the Superiority of Plant Molecules and Importance of Animal Foods
- Refutation of plant molecules' overall net benefit and assertion of negative side effects
- Discussion on obtaining essential nutrients like B12, vitamin K2, and others from animal foods
- Study comparison showing no significant clinical differences in outcomes between low and high fruit/vegetable diets
Historical Importance of Eating Organs and Indigenous Practices
- Discussion about the traditional practice of consuming organs in indigenous cultures
- Anecdotes of trappers getting sick from lack of organ consumption leading to their death
- Exploration of how indigenous cultures and animals utilize all parts of the animal for nutrition
Cultural Significance and Nutrition of Various Animal Organs
- Information on the nutritious value and cultural preferences of various animal organs
- Examples of Arctic explorer's insights into organ consumption
- Experiences and reflections on consuming different organs like liver, brain, and gallbladder
Ethical Considerations of Factory Farming and Regenerative Agriculture
- Discussion on the ethical concerns of force-feeding ducks for foie gras and the legality of certain practices in factory farming
- Comparison between the treatment of ducks and the treatment of livestock in factory farms
- Debate on the sustainability and benefits of grass-fed, grass-finished meat versus grain-fed cows
Regenerative Agriculture for Soil Health and Sustainability
- Exploration of regenerative agriculture's impact on soil health and carbon sequestration
- Discussion on the synergistic relationship between animals, soil, and nutrients
- Consideration of the historical impact of monocropping and the potential of regenerative farming practices
Exploring the Comanche Culture and Ketosis Benefits
- Insight into the diet and lifestyle of the Comanche tribe, primarily meat-based with occasional berries, emphasizing the benefits of a fat-rich diet for long-term sustenance and endurance
- Discussion on the advantages of ketosis in the human body, including the ability to switch between fat metabolism and glucose metabolism, and the benefits of intermittent fasting
- Explanation of how ketosis triggers cellular house cleaning processes, promoting the removal of damaged cells, proteins, and mitochondria which are essential for overall health and wellness
Hunter-Gatherer Dietary Shifts and Modern Nutrition Considerations
- Reflecting on the dietary transitions of modern hunter-gatherer tribes due to environmental changes and scarcity of big animals, and how it impacts their food choices
- Discussion on the preference for animal-based foods in ancestral diets, along with occasional tubers, and the implications for balanced nutrition in the modern context
- Insights into human metabolic flexibility, highlighting the importance of cyclic ketosis over persistent ketosis, and the role of gluconeogenesis in producing glucose from proteins in the absence of carbohydrates
Effects of Carnivore Diet on Energy Levels and Weight Loss
- Discussion on the impact of consuming a total animal diet on energy levels and sustained energy throughout the day
- Observations on the lack of significant energy crashes and consistent energy levels experienced while on the carnivore diet
- Significant weight loss, improved energy, increased aggression, and positive physiological changes noted during the month on the carnivore diet
Exploration of Autoimmune Conditions and Plant-based Diet Effects
- Discussion on the potential role of plant toxins triggering autoimmune reactions, specifically in conditions like vitiligo, eczema, and asthma
- Experiments with incorporating less toxic carbohydrates incl. honey and fruit, resulting in improved health outcomes and better sleep
- Insights into the benefits of honey, contrasting it with processed sugars and its potential positive effects on oral health and oxidative stress
Hadza Tribe's Diet and Observations on Tooth Decay
- Women in Hadza tribe stop digging tubers when there's abundant meat
- Discussions about baobab fruit and honey consumption in the tribe
- Findings on tooth decay comparing men and women in the Hadza tribe
Effects of Fructose, Satiety Mechanisms, and Plant Toxicity Spectrum
- Biochemical differences between fructose and glucose
- Discussion on satiety mechanisms related to different diets
- Insights into plant toxicity and examples of toxic plant parts
Vegans, Health, and Dietary Choices
- Discussion on the ideology and lifestyle choice of veganism
- Contrast between healthy and unhealthy vegans in terms of physical appearance and diet
- Exploration of intentional dietary choices and their impact on health
Impact of Processed Oils and Dietary Trends
- Analysis of the rise in chronic diseases and obesity in the context of dietary changes
- Examination of factors like smoking rates and exercise levels in relation to disease prevalence
- Discussion on meat consumption, vegetable oils, and the role of saturated fats in diet
Impact of Vegetable Oils on Fat Cells and Health
- Discussion on how polyunsaturated fats in vegetable oils affect fat cells in the body
- Explanation of how excess linoleic acid may lead to adipocyte hypertrophy
- Insights on the evolutionary inconsistency of current vegetable oil consumption
Sugar Industry Influence and Health Implications
- Examination of the sugar industry's role in shifting blame to unsaturated fats
- Importance of understanding the impact of processed foods and vegetable oils on health
- Discussion on the narrative surrounding fat consumption and its association with heart disease
Benefits of Organ Capsules and Grass-Fed Animals
- Discussion on the advantages of capsules for consuming organs and their portability
- Emphasis on the quality of organ supplements made from grass-fed animals
- Plans for developing a regenerative chain involving grass-fed animals in the US
Dietary Habits, Fasting, and Exercise Regimen
- Details of the daily eating routine, focusing on intermittent fasting and meal timings
- Exploration of benefits of early dinner for improved sleep and hormonal balance
- Description of exercise routine involving Pavel Tsatsouline's 'Grease the Groove' method and strength training approach
Understanding Cholesterol: LDL and HDL
- Discussion on the misconception about saturated fats and LDL cholesterol
- Importance of cholesterol in human diet for hormone production and health
- Exploration of the roles of LDL and HDL in the immune system
Debunking the Standard Lipid Hypothesis
- Critique of the standard belief that LDL is bad and HDL is good
- Analysis of the flaws in the lipid hypothesis due to incomplete considerations of HDL levels
- Insight into the complexity of LDL-HDL ratio and metabolic health
The Lipid Energy Model and LDL Movement in Response to Fasting
- Discussion on the lipid energy model developed by Dave addressing the movement of LDL in response to burning fat as energy.
- Debunking the traditional idea that LDL elevation during fasting leads to atherosclerosis, drawing parallels to hibernating mammals like bears.
- Exploration of the misconceptions regarding LDL's role in atherosclerosis, hinting at a potential third variable affecting the correlation.
Contextual Variables in Understanding LDL and Atherosclerosis
- Criticizing the oversimplified view of LDL causing atherosclerosis and highlighting the importance of metabolic health in interpreting cholesterol markers.
- Discussion on the disparity in atherosclerosis development between arteries and veins, suggesting endothelial damage as a crucial factor.
- Challenging the mainstream belief on LDL levels and heart disease, emphasizing the need to consider individual metabolic contexts.
Understanding Atherosclerosis and LDL Particles
- Explanation of the layers involved in atherosclerosis development and the role of macrophages
- Discussion on the impact of LDL particles on atherosclerosis formation and the potential role of oxidized LDL
- Exploration of factors like linoleic acid and oxidative stress in LDL oxidation and its relation to arterial plaque
Debating LDL and HDL with Mainstream Medical Ideas
- Conversation about debates with mainstream medical professionals regarding LDL and HDL
- Mention of studies showing the impact of linoleic acid on LDL oxidation and quality
- Critique of the focus on LDL alone in medical recommendations and the importance of considering metabolic health and context
Debunking Common Perceptions About Fiber and Its Impact on Digestion
- Discussion on the misconception that fiber is essential for a healthy digestive system
- Reference to a study showing complete resolution of idiopathic constipation in a group with zero fiber intake
- Consideration of factors like dysbiosis and inflammation in relation to constipation
Optimal Dietary Recommendations for Overall Health and Well-being
- Advocacy for a diet centered on meat and organs from well-raised animals
- Suggestion to eliminate toxic plants, vegetable oils, and processed sugars
- Acknowledgement of the mainstream medical establishment's differing views and the mission to challenge existing dietary norms
The Spiritual and Ethical Aspects of Hunting and Connecting with Food
- Discussion on the spiritual experience and responsibility involved in hunting and taking a life respectfully
- Exploration of the deep connection to food and nature through hunting experiences
- Emphasis on the difference between hunting for sustenance and store-bought meat, highlighting the spiritual and ethical perspectives
The Discipline and Rewards of Hunting as a Sustainable and Athletic Pursuit
- Consideration of hunting as a discipline and sustainable way of sourcing food, challenging the norm of store-bought options
- Discussion on the physical and mental challenges of hunting, likening it to an athletic pursuit requiring dedication and endurance
- Highlighting the satisfaction and unique connection to food and nature that comes from hunting, contrasting it with modern food consumption practices
The Thrill of Bow Hunting and Connecting with Nature
- Discusses the unique experience and adrenaline rush of bow hunting for animals
- Shares a personal story of sprinting to position for a clean shot on an elk
- Reflects on the primal instinct and flow state achieved during bow hunting and being in the wilderness
Digital Age vs. Connection to Nature
- Explores the disconnect caused by excessive digital immersion and urbanization
- Emphasizes the rejuvenating effects of being in nature and the beauty of wilderness
- Raises concerns about the potential future of human evolution towards excessive technology reliance
Benefits of Grass-Fed, Grass-Finished Meat
- Discussion on the nutritional benefits of grass-fed, grass-finished meat over grain-fed
- Examination of what grass-fed animals are not exposed to, like plastic, waste products, and cookies
- Exploration of the ethical and ecosystem benefits of consuming grass-fed, grass-finished meat
Creatine and Brain Performance
- Investigation into the role of creatine in brain performance and supplementation benefits
- Consideration of studies showing improved memory in vegetarians with creatine supplements
- Discussion on the impact of creatine on muscle strength and the need for supplementation in plant-based diets
Evolution of Human Brain Size and Impact of Hunting
- Discussion on the size of the human brain based on cranial vault size and the theories behind the evolution of brain size
- Importance of hunting in human evolution and the correlation between hunting and brain growth
- Exploration of the role of tools, hunting, and nutrient intake in shaping human evolution
Psychedelics and Human Consciousness
- Conversation about the impact of psychedelics on human consciousness and creativity
- Personal experience with psilocybin and its profound effects on perception and connection with nature
- Reflection on the medicinal and transformative potential of psychedelics in therapeutic settings