JRE MMA Show #53 with Jeff Novitzky

Episode Timestamps

• 00:00:00

  John Jones Initial Failed Test & Arbitration with Richard McLaren

  • John Jones tested positive for a long-term metabolite in 2017, source unknown.
  • A full arbitration hearing led by Richard McLaren determined violation was unintentional.
  • No performance-enhancing benefit detected from the substance found in Jones' system.
• 00:01:29

  Understanding Long-term Metabolites & Pulsing Effects

  • Discussion on the pulsing effect of long-term metabolites after ingestion.
  • Exploration of the presence of metabolites in fat tissues and their detectability.
  • Comparison of short and medium-term metabolites with the long-term M3 metabolite in John's case.
• 00:11:54

  John's Picogram Readings: Detection and Small Amounts

  • John's picogram levels were discussed, starting at 80 picograms on July 28th, 2017.
  • The accuracy of measuring picogram levels was highlighted, with a margin of error of 20-60 picograms.
  • Larry Bowers, an anti-doping expert, emphasized the challenges in analyzing such small concentrations.
• 00:15:29

  Terenobol and Detection Challenges

  • Introduction to Larry Bowers, an anti-doping expert with significant experience.
  • Discussion on the detection window for long-term metabolites and challenges in studying illegal substances like DHCMT.
  • Exploring the differences between straight Terenobol and oral Terenobol, emphasizing the importance of accurate substance comparison.
• 00:22:38

  Clomaphenes Study on Excretion Rates and Chlorinated Substance

  • Clomaphenes and oral Tyrinobol both contain a chlorine atom on the molecule.
  • Study on clomaphenes excretion rates showed a pulsing effect in urine samples.
  • Presence of chlorinated substance in adipose tissue could lead to excretion.
• 00:24:31

  Discussion on Weight Cuts and Microdosing Endogenous Substances

  • Exploration of extreme weight gains and cuts in UFC athletes compared to Olympic wrestling.
  • Microdosing commonly done with endogenous substances for avoiding detection.
  • Concerns and strategies related to microdosing performance-enhancing drugs.
• 00:33:54

  Concerns about Anabolic Agents and Anti-Doping Violations

  • Detection levels for anabolic agents like Terenobol are a subject of concern, with labs seeking to surpass minimum standards set by WADA.
  • The discussion involves notable figures like Frank Meir and UFC regulations mirroring WADA's anti-doping code.
  • Experts emphasize the challenges in determining re-administration and the importance of fair testing protocols.
• 00:36:22

  Debate on Long-term Metabolites and Anti-Doping Measures

  • Research on metabolites like DHCMT raises questions about testing accuracy and substance re-administration.
  • Prominent names such as Dr. Daniel Eichner provide insights on metabolite interpretations and residual amounts.
  • The focus shifts to WADA's proposed thresholds for low-level substances to address contamination concerns.
• 00:46:12

  Doping Cases and Testing Scenarios in Athletics

  • Discussion on cases of positive doping tests in athletics due to unexpected sources like lip balm.
  • Comparison of different doping cases, including skier testing positive for anabolic agent and MMA fighters' instances.
  • Exploration of the complexity of testing thresholds and unintentional ingestion in doping cases.
• 00:50:54

  Implementation of Anti-Doping Programs by UFC with USADA Collaboration

  • Role of the speaker in developing anti-doping programs for UFC after working with USADA on PED cases.
  • Clarification on the misconception of speaker working directly for USADA.
  • Insight into the cooperation between UFC and USADA to enforce doping regulations in sports.
• 00:57:47

  Athletes and Substance Usage

  • Differentiation between intentional cheating and naive supplement choices discussed
  • Examples provided including cases of Josh and Tim
  • Importance of strict liability provisions to prevent misuse of prohibited supplements
• 00:59:50

  Testing Procedures and Jurisdiction

  • Use of clearing house for athlete testing records explained
  • Specific case of john's test results and metabolite levels analyzed
  • Discussion on Nevada State Athletic Commission's jurisdiction and handling of the situation
• 01:09:40

  Commissioner Andy Foster and USADA's Familiarity with John's Case

  • Commissioner Andy Foster and the California commission had prior knowledge of John's case due to two public hearings
  • They were critical of USADA's handling and expressed doubts regarding the performance-enhancing benefit
  • USADA and California commission were already acquainted with the drug dynamics and long-term metabolites
• 01:12:08

  Challenges and Fairness in Dealing with John's Situation

  • Immediate challenges arose close to the fight due to the positive test results
  • Navigating the optics and criticism surrounding the issue while ensuring fairness for the fighters
  • Discussions around preventing similar situations in the future through increased testing frequency
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• 01:32:03

  Discussion about DHCMT Testing and Implications

  • Debate on the fairness of preventing fight based on DHCMT testing and Dr. Daniel Eichner's statement.
  • Importance of increased volume of testing and directing athletes towards approved supplements.
  • Analysis of detection methods and sensitivity improvement over the last five years.
• 01:36:27

  John Jones' Compliance and Theoretical Considerations

  • John Jones' consistent compliance with testing and lack of whereabouts strikes according to USADA.
  • Discussion on past incidents and arguments for and against his behavior during the suspension.
  • Consideration of the influence of surrounding individuals on fighters' decision making and advice.
• 01:43:14

  Steve's Incredible Presence in Las Vegas & Daughter's Artistic Gift

  • Witnessed Steve controlling a crowd in Las Vegas without physical contact
  • Received sculpted beer mugs with references to Golden Snitch Brewing from his daughter
  • Surprised with a box of unique t-shirts featuring Golden Snitch logo
• 01:45:17

  Exclusive Shirt Reveal in Moscow and Special Studies Discussion

  • Pictures taken at KGB or FSB headquarters in Moscow revealed on social media
  • Received exclusive shirts with interest shown by online audience
  • Discussed scientific studies and decisions in UFC with valuable insights