#1108 - Peter Attia

Episode Timestamps

• 00:00:00

  Exploring the Limits of Human Endurance in Swimming

  • Penny Dean holds the fastest record for swimming the Catalina Channel.
  • Discussion on women's advantages in marathon swimming due to physiology.
  • The mental and physical challenges of long-distance swimming are immense.
• 00:05:50

  The Emotional Journey of Long-Distance Open Water Swimming

  • Swimming in the ocean presents both physical challenges and emotional highs.
  • Experiencing bio-luminescence adds to the beauty and thrill of night swims.
  • The risks of open water swimming are highlighted by recent shark attacks.
• 00:14:55

  Nighttime Swim Encounter with Sharks and Island Ecosystems

  • Swimmer recounts a terrifying nighttime encounter with a shark near Santa Rosa Island.
  • Discussion on shark deterrent technologies and their effectiveness during swimming.
  • Exploration of Catalina Island's unique ecosystem and invasive species management.
• 00:23:47

  Human-Animal Interaction and Wildlife Management Insights

  • Discussion on aggressive animal behavior and human interactions with wildlife.
  • Examples of wildlife adapting to human environments and feeding habits.
  • Concerns about wildlife management and population control in urban areas.
• 00:33:41

  Discussion on Coyotes, Jocko Willink, and Sniper Skills

  • Coyotes demonstrate remarkable intelligence and adaptability in urban environments.
  • The conversation highlights the impressive skills of Navy SEAL snipers.
  • Connections to influential figures like Jocko Willink and Tim Ferriss are explored.
• 00:42:37

  The Art and Science of Archery and Shooting

  • Archery is compared to meditation, emphasizing focus and technique.
  • The significance of trigger control in shooting is discussed extensively.
  • Experiences in hunting reveal the connection between survival instincts and archery.
• 00:54:29

  Exploring the Benefits of Intermittent Fasting and Nutrition

  • Intermittent fasting can enhance metabolic efficiency and energy levels.
  • Long-term dietary choices impact overall health and energy management.
  • Personal experiences reveal the complexities of nutritional habits over time.
• 01:05:12

  Exploring Caloric Restriction and Longevity through Rapamycin

  • Caloric restriction has been shown to extend lifespan across various organisms.
  • Rapamycin may enhance longevity by targeting nutrient-sensing pathways.
  • Studies indicate dietary restriction impacts lifespan, even with poor diets.
• 01:14:50

  Exploring Rapamycin's Impact on Immunity and Metabolism

  • A study shows rapamycin can enhance immune response in older adults.
  • Higher doses of rapamycin lead to significant side effects like mouth sores.
  • Historical context reveals the evolution of anesthesia from cocaine to modern methods.
• 01:26:23

  Exploring Muscle Recovery and Training Adaptations

  • Discussed the significance of muscle biopsies in understanding metabolic health.
  • Highlighted the role of eccentric training in athletic performance enhancement.
  • Examined the implications of strength training for endurance athletes.
• 01:37:33

  Exploring the Science of Marathon Running and Performance

  • Marathon training emphasizes strength and cadence for optimal performance.
  • Genetic predispositions play a role in athletic capabilities and performance.
  • Doping controversies and their implications in competitive sports are discussed.
• 01:47:50

  The Impact of Doping in Professional Cycling and Longevity

  • Professional cyclists face extreme physiological demands leading to significant health risks.
  • Doping regulations create a complex debate on fairness and performance enhancement.
  • Cardiovascular health issues are prevalent among highly trained athletes despite their fitness.
• 02:03:30

  Exploring Growth Hormone and Its Impacts on Longevity

  • The research on growth hormone's effects on longevity is complex and evolving.
  • A significant portion of scientific literature is not cited, questioning its relevance.
  • The conversation highlights the need for careful analysis of hormone therapies.
• 02:13:39

  Exploring Longevity and Health Improvements Through Science

  • Life expectancy has improved significantly since 1967 due to various health advancements.
  • Dietary changes, especially carbohydrate reduction, can drastically affect health outcomes.
  • Scientific understanding of human biology is evolving, leading to better longevity strategies.
• 02:22:54

  Exploring the Complexities of Weight Loss and Metabolism

  • Weight loss involves intricate metabolic processes and genetic factors affecting individuals.
  • Dietary changes and hormone manipulation play crucial roles in effective weight management.
  • Understanding the root causes of weight issues can enhance patient treatment approaches.
• 02:32:27

  Exploring the Complex Relationship Between Diet, Hormones, and Stress

  • Cortisol levels significantly impact weight loss and fat gain.
  • Dietary habits are influenced by stress and hormonal responses.
  • Time-restricted feeding may help manage eating patterns and hormone levels.
• 02:42:57

  Exploring Passion for Archery and Life-Long Learning

  • The speaker shares insights about archery and its discipline.
  • Life experiences shaped a diverse career in medicine and engineering.
  • Personal growth through hobbies like race car driving and archery is emphasized.